10-Year Historical Development of Dual Layer Hollow Fiber Hemodialysis Membranes
DOI:
https://doi.org/10.11113/amst.v27n1.258Keywords:
Dual layer hollow fiber, hemodialysis, mixed matrix membrane, adsorption process, diffusion processAbstract
Hollow fiber membranes have been employed to purify blood from within the heart of hemodialysis process, namely dialyzer. In the past 10 years, the interest on the utilization of dual layer hollow fiber (DLHF) membranes has arisen due to the innovative idea of combining adsorption and diffusion processes into one step. This short review outlines the historical development of DLHF hemodialysis membranes that spans from year 2012 to year 2022. The motivation and the outcome from the first and the second generation DLHF hemodialysis membranes are discussed. In addition, the use of DLHF membranes in other hemodialysis-related application is presented. This short review would provide a perspective for membranologists to recognize the issues in DLHF hemodialysis membranes and to work their way to finding the real solutions.
References
N. Said, W. J. Lau, Y. C. Ho, S. K. Lim, M. N. Zainol Abidin, A. F. Ismail. 2021. A review of commercial developments and recent laboratory research of dialyzers and membranes for hemodialysis application. Membranes (Basel). 11: 1-38. https://doi.org/10.3390/membranes11100767.
K. Y. Lin, C. S. Liang, C. C. Hsu, S. L. Lin, Y. T. Chen, F. S. Huang, S. L. Wang, J. S. Jang, Y. W. Lu. 2022. Optoelectronic online monitoring system for hemodialysis and its data analysis. Sensors Actuators B Chem. 364: 131859. https://doi.org/10.1016/j.snb.2022.131859.
Y. Raharjo, M. N. Z. Abidin, A. F. Ismail, M. Z. Fahmi, Saiful, M. Elma, D. Santoso, H. Haula’, A. R. Habibi. 2022. Dialysis membranes for acute kidney injury. Membranes (Basel). 12: 1-15. https://doi.org/10.3390/membranes12030325.
N. Said, M. Nidzhom, Z. Abidin, H. Hasbullah, A. F. Ismail, P. S. Goh, M. Ha, D. Othman, M. S. Abdullah, B. C. Ng, S. Hamimah, S. Abdul, F. Kamal. 2019. Iron oxide nanoparticles improved biocompatibility and removal of middle molecule uremic toxin of polysulfone hollow fi ber membranes, 48234: 1-13. https://doi.org/10.1002/app.48234.
O. E. M. ter Beek, M. K. van Gelder, C. Lokhorst, D. H. M. Hazenbrink, B. H. Lentferink, K. G. F. Gerritsen, D. Stamatialis. 2021. In vitro study of dual layer mixed matrix hollow fiber membranes for outside-in filtration of human blood plasma. Acta Biomater. 123: 244-253. https://doi.org/10.1016/j.actbio.2020.12.063.
W. Cheah, Y. Sim, F. Yeoh. 2016. Amine-functionalized mesoporous silica for urea adsorption. Mater. Chem. Phys. 175: 1-7. https://doi.org/10.1016/j.matchemphys.2016.03.007.
S. Yamamoto, T. Ito, M. Sato, S. Goto, J. J. Kazama, F. Gejyo, I. Narita. 2019. Adsorption of protein-bound uremic toxins using activated carbon through direct hemoperfusion in vitro. Blood Purif. 48: 215-222. https://doi.org/10.1159/000500014.
E. Devine, D. H. Krieter, M. Rüth, J. Jankovski, H. D. Lemke. 2014. Binding affinity and capacity for the uremic toxin indoxyl sulfate. Toxins (Basel). 6: 416-430. https://doi.org/10.3390/toxins6020416.
M. S. L. Tijink, M. Wester, J. Sun, A. Saris, L. a M. Bolhuis-Versteeg, S. Saiful, J. a Joles, Z. Borneman, M. Wessling, D. F. Stamatialis. 2012. A novel approach for blood purification: mixed-matrix membranes combining diffusion and adsorption in one step. Acta Biomater. 8: 2279-87. https://doi.org/10.1016/j.actbio.2012.03.008.
M. S. L. Tijink, M. Wester, G. Glorieux, K. G. F. Gerritsen, J. Sun, P. C. Swart, Z. Borneman, M. Wessling, R. Vanholder, J. a Joles, D. Stamatialis. 2013. Mixed matrix hollow fiber membranes for removal of protein-bound toxins from human plasma. Biomaterials. 347819-28. https://doi.org/10.1016/j.biomaterials.2013.07.008.
D. Pavlenko, E. Van Geffen, M. J. Van Steenbergen, G. Glorieux. 2016. New low-flux mixed matrix membranes that offer superior removal of protein-bound toxins from human plasma. Nat. Publ. Gr. 1-9. https://doi.org/10.1038/srep34429.
Saiful, Z. Borneman, M. Wessling. 2018. Double layer mixed matrix membrane adsorbers improving capacity and safety hemodialysis. IOP Conf. Ser. Mater. Sci. Eng. 352: 3-9. https://doi.org/10.1088/1757-899X/352/1/012048.
I. Geremia, R. Bansal, D. Stamatialis. 2019. In vitro assessment of mixed matrix hemodialysis membrane for achieving endotoxin-free dialysate combined with high removal of uremic toxins from human plasma. Acta Biomater. 90: 100-111. https://doi.org/10.1016/j.actbio.2019.04.009.
I. Geremia, D. Pavlenko, K. Maksymow, M. Rüth, H. D. Lemke, D. Stamatialis. 2020. Ex vivo evaluation of the blood compatibility of mixed matrix haemodialysis membranes. Acta Biomater. 111: 118-128. https://doi.org/10.1016/j.actbio.2020.05.016.
D. L. Kim, D. Stamatialis. 2020. High flux mixed matrix membrane with low albumin leakage for blood plasma detoxification. J. Memb. Sci. 609: 118187. https://doi.org/10.1016/j.memsci.2020.118187.
S. Mansur, M. Hafiz, D. Othman, M. Nidzhom, Z. Abidin, N. Ahmad, N. Nik, A. Fauzi, S. Hamimah, S. Abdul, P. Sean, M. Sohaimi, M. Hariz. 2022. Dual-layer hollow fibre haemodialysis membrane for effective uremic toxins removal with minimal blood-bacteria contamination. Alexandria Eng. J. 61: 10139-10152. https://doi.org/10.1016/j.aej.2022.03.043.
S. Mansur, M. H. D. Othman, M. N. Z. Abidin, A. F. Ismail, S. H. S. Abdul Kadir, P. S. Goh, H. Hasbullah, B. C. Ng, M. S. Abdullah, R. Mustafar. 2021. Enhanced adsorption and biocompatibility of polysulfone hollow fibre membrane via the addition of silica/alpha-mangostin hybrid nanoparticle for uremic toxins removal. J. Environ. Chem. Eng. 9: 106141. https://doi.org/10.1016/j.jece.2021.106141.
O. E. M. ter Beek, M. K. van Gelder, C. Lokhorst, D. H. M. Hazenbrink, B. H. Lentferink, K. G. F. Gerritsen, D. Stamatialis. 2021. In vitro study of dual layer mixed matrix hollow fiber membranes for outside-in filtration of human blood plasma. Acta Biomater. https://doi.org/10.1016/j.actbio.2020.12.063.
M. N. Z. Abidin, P. S. Goh, N. Said, A. F. Ismail, M. H. D. Othman, M. S. Abdullah, B. C. Ng, H. Hasbullah, S. H. Sheikh Abdul Kadir, F. Kamal, S. Mansur. 2020. Polysulfone/amino-silanized poly(methyl methacrylate) dual layer hollow fiber membrane for uremic toxin separation. Sep. Purif. Technol. 236. https://doi.org/10.1016/j.seppur.2019.116216.
M. N. Zainol Abidin, P. S. Goh, N. Said, A. F. Ismail, M. H. D. Othman, H. Hasbullah, M. S. Abdullah, B. C. Ng, S. H. Sheikh Abdul Kadir, F. Kamal, S. Mansurz. 2020. Co-Adsorptive removal of creatinine and urea by a three-component dual-layer hollow fiber membrane. ACS Appl. Mater. Interfaces. 12: 33276-33287. https://doi.org/10.1021/acsami.0c08947.
I. Geremia, J. A. W. Jong, C. F. van Nostrum, W. E. Hennink, K. G. F. Gerritsen, D. Stamatialis. 2021. New mixed matrix membrane for the removal of urea from dialysate solution, Sep. Purif. Technol. 277: 119408. https://doi.org/10.1016/j.seppur.2021.119408.
M. De Pascale, M. G. De Angelis, C. Boi. 2022. Mixed matrix membranes adsorbers (MMMAs) for the removal of uremic toxins from dialysate. Membranes (Basel). 12: 1-21. https://doi.org/10.3390/membranes12020203.
Downloads
Published
How to Cite
Issue
Section
License
Copyright of articles that appear in Journal of Applied Membrane Science & Technology belongs exclusively to Penerbit Universiti Teknologi Malaysia (Penerbit UTM Press). This copyright covers the rights to reproduce the article, including reprints, electronic reproductions, or any other reproductions of similar nature.